Professional and Linguistic Assessments Board (PLAB) Practice Exam

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What is commonly prescribed for managing pregnancy-related constipation?

Psyllium husk
Bisacodyl
Lactulose
Magnesium hydroxide

The correct answer is: Lactulose

Lactulose is commonly prescribed for managing pregnancy-related constipation primarily due to its safety profile and effectiveness. It is a synthetic disaccharide that acts as an osmotic laxative; it increases the water content and volume of the stool, promoting bowel movements without stimulating the uterus or causing undue strain, which is particularly important during pregnancy. When considering other options, while psyllium husk is a fiber supplement that can aid in softening stools, it may not be as well tolerated or effective in all patients compared to lactulose. Bisacodyl, on the other hand, is a stimulant laxative that may pose risks as it stimulates peristalsis and can lead to abdominal pain or cramping, which may be undesirable in pregnant patients. Magnesium hydroxide, while also effective as an osmotic laxative, can cause diarrhea and may lead to electrolyte imbalances if not used carefully during pregnancy. In summary, lactulose’s gentle action and safety make it a preferred choice for managing constipation in pregnant individuals, ensuring that both maternal and fetal health are considered in treatment.