Professional and Linguistic Assessments Board (PLAB) Practice Exam

What is the preferred method of birth control for patients with sickle cell disease?

1. Oral contraceptives

2. Condoms

3. Depot medroxyprogesterone acetate

4. Intrauterine devices

The correct answer is: Depot medroxyprogesterone acetate

The preferred method of birth control for patients with sickle cell disease is depot medroxyprogesterone acetate. This method of contraception is advantageous for several reasons, particularly in the context of managing sickle cell disease. Depot medroxyprogesterone acetate is a progestin-only contraceptive that is administered via an injection every three months. One of its key benefits for women with sickle cell disease is that it reduces menstrual bleeding and can help minimize the risk of anemia, which is a crucial consideration since patients with this condition already face challenges related to blood health. The reduced frequency and volume of menstrual bleeding can help maintain hemoglobin levels and overall well-being. Additionally, since depot medroxyprogesterone acetate does not contain estrogen, it is a safer choice for women with sickle cell disease, as estrogen-containing contraceptives may increase the risk of thromboembolic events, which individuals with this condition are already predisposed to. The other methods listed, such as oral contraceptives and intrauterine devices, may not offer the same degree of safety or effectiveness in addressing the specific health challenges associated with sickle cell disease. For instance, while oral contraceptives can be effective, the presence of estrogen might pose risks