Professional and Linguistic Assessments Board (PLAB) Practice Exam

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What is the primary treatment class for managing symptoms of diabetic neuropathy?

SSRIs
Anticonvulsants
NSAIDs
Beta-blockers

The correct answer is: Anticonvulsants

The primary treatment class for managing symptoms of diabetic neuropathy is indeed anticonvulsants. These medications are frequently utilized in this context due to their effectiveness in relieving neuropathic pain. Anticonvulsants, such as gabapentin and pregabalin, work by stabilizing electrical activity in the nervous system and inhibiting pain signals. This mechanism can help to alleviate the burning, tingling, and shooting pains that patients often experience with diabetic neuropathy. In contrast, while SSRIs may offer some benefit for managing mood disorders and certain pain syndromes, they are not primarily indicated for diabetic neuropathy. NSAIDs are generally used for inflammatory pain and may not effectively address the specific pain associated with neuropathy. Beta-blockers primarily target cardiovascular conditions and are not indicated for the treatment of neuropathic pain. Therefore, for diabetic neuropathy, anticonvulsants represent the most appropriate and effective treatment class.