Professional and Linguistic Assessments Board (PLAB) Practice Exam

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What should be administered along with lorazepam in case of status epilepticus?

Thiamine
D50
Both A and B
Only an anticonvulsant

The correct answer is: Both A and B

In the management of status epilepticus, it is crucial to administer thiamine along with lorazepam. This is because patients with a history of alcohol use disorder or malnutrition may be at risk for Wernicke's encephalopathy, a serious neurological condition caused by thiamine deficiency. By providing thiamine, healthcare providers can help prevent this complication. Additionally, administering D50 (a glucose-containing solution) is important for patients who may have hypoglycemia, which can also precipitate or exacerbate seizures. Providing glucose helps stabilize the patient's metabolic state and ensures that the brain has the necessary energy to function properly. Thus, giving both thiamine and D50 along with lorazepam not only addresses the immediate seizure activity but also safeguards the patient against potential complications related to nutritional deficits and hypoglycemia. This comprehensive approach is essential in the emergency management of status epilepticus.