Professional and Linguistic Assessments Board (PLAB) Practice Exam

Which drug is commonly used to treat menstrual pain in young women?

1. Naproxen

2. Mefenamic acid

3. Diclofenac

4. Promethazine

The correct answer is: Mefenamic acid

Mefenamic acid is a nonsteroidal anti-inflammatory drug (NSAID) that is often used for the relief of menstrual pain, also known as dysmenorrhea. It works by inhibiting the production of prostaglandins, which are compounds that play a key role in the pain signaling associated with menstruation. By reducing prostaglandin levels, mefenamic acid helps alleviate cramping and discomfort during menstrual cycles. This medication is particularly suitable for young women who experience moderate to severe menstrual pain, as it is effective in targeting the underlying inflammatory processes. It is usually taken at the onset of menstrual symptoms to provide prompt relief. While other NSAIDs, such as naproxen and diclofenac, are also effective for treating menstrual pain, mefenamic acid is frequently highlighted in clinical guidelines specifically for this purpose due to its established efficacy and safety profile in younger populations. Promethazine, on the other hand, is primarily an antihistamine used for nausea, vomiting, and allergy symptoms rather than for menstrual pain.