Professional and Linguistic Assessments Board (PLAB) Practice Exam

Which of the following best describes dermatitis herpetiformis?

1. Lesions that occur in clusters and are itchy

2. Non-itchy papules with anti-IGA elevation

3. Blisters formed in groups without redness

4. Scaly patches located on elbows and knees

The correct answer is: Lesions that occur in clusters and are itchy

Dermatitis herpetiformis is a chronic skin condition characterized by the presence of extremely itchy lesions. The hallmark of this condition is the formation of clusters of small vesicles or papules that often appear symmetrically on the body, particularly on the elbows, knees, buttocks, and scalp. The intense itching and the clustered arrangement of the lesions are key features that help distinguish it from other skin disorders. The presence of itchiness is significant as it reflects the autoimmune nature of the condition, which is associated with gluten sensitivity and often seen in individuals with celiac disease. The clustered nature of the lesions also aligns with how the skin responds to the underlying immunological processes.